For Power Users is the Twitter Client Yoru Fukurou interesting, a free App from Japan. For the range of functions include, for example, Search Tabs, support for multiple Accounts and different view modes. You can upload images, Links, shorten, and addresses by Bookmarklet add.
Tabs from which you can make lists, or create rules, even regular expressions are supported. Notify you about new messages by a tone or Growl. Pictures shows the Tool in a separate window, it's translated Tweets in the German language, and lists the API errors in a console.
YoruFukurou screenshots
You can free download YoruFukurou 32, 64 bit and safe install the latest trial or new full version for Windows 10 from the official site.